Defective cilia linked to heart valve birth defects

Defective cilia linked to heart valve birth defects

Bicuspid aortic valve (BAV) is most common heart valve defect one most common defects Defective cilia linked any type, two leaflets are fused together, valves eventually will be replaced or repaired heart surgery. A team researchers at Medical South Carolina (MUSC) discovered that a mutation a gene controlling cilia, are linked development BAV. an article published online 7, team used models human data reveal that BAV disease aortic valve narrowing are by disruption defects cilia.

A physician and surgeon performed the hospital’s first transcatheter aortic valve replacement (TAVR) last month. The method is an alternative to open heart surgery. Instead of making a large incision in the chest, a catheter is instead inserted into one of the leg arteries that acts as a conduit for the new valve. “Our TAVR program is the result of two years of planning and hard work to offer our patients the most advanced treatment option for valve replacement,”said Adam Groshans, president aortic valve stenosis treatment without surgery of Mercy Health Springfield, in a news release. “I congratulate the entire heart care team on this achievement. ” MORE: How did your district do on the 2018-19 state report card? Hospital officials said as part of the procedure, the new valve is compressed tightly onto a balloon and is advanced through the catheter to the diseased valve. It is put in place when the balloon is inflated. “The new valve is immediately functional and most patients experience instant clinical benefit,” the release said.

In a TAVI procedure, flexible The doctor then catheter Springfield hospital adds into artery at top Replacing a tight thigh and threads up to opening heart and Once reaches diseased aortic valve.

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